Scientific Research Projects
The Faculty of Medicine actively participates in scientific research through individual and interdisciplinary projects in the field of medical sciences. Research is conducted with the support of various levels of government and focuses on current health issues, therapy development, and the advancement of diagnostic and therapeutic methods.
1. Forensic Significance of Multiple Analyses in Detecting Primary and Secondary Hypothermia as a Cause of Death
Project Lead: Prof. Dr. Adis Salihbegović, Department of Forensic Medicine
This project aims to improve forensic practice in cases of death related to extreme temperatures and possible intoxication. By analyzing non-specific but frequent diagnoses, the goal is to enhance diagnostic accuracy and healthcare system education.
2. Correlation of p53 and Bcl-2 Proliferative Biomarker Expression with the Mutation Status of Tumor Cell Lines in Patients Diagnosed with Basal Cell Carcinoma
Project Lead: Prof. Dr. Azra Metović, Department of Medical Biology and Human Genetics
The project investigates p53 and Bcl-2 biomarkers and genetic mutations in patient tissue to improve diagnostics and targeted therapy for basal cell carcinoma.
3. Validation of the Association Between General and Malondialdehyde-Linked Humoral Immune Response and Complement System Activation Parameters with Graft Rejection in Kidney Transplant Patients
Project Lead: Assist. Prof. Dr. Lejla Alić Mehić, Department of Medical Biochemistry
The project examines the impact of gene polymorphisms for factor H and related proteins on kidney graft survival and complement system activation. Results will contribute to understanding immune mechanisms of graft rejection and support the establishment of the first complement research laboratory in Bosnia and Herzegovina.
4. Neuroprotective Effects of Curcumin in Perinatal Asphyxia
Project Lead: Assist. Prof. Dr. Sanita Maleškić Kapo, Department of Pharmacology, Toxicology and Clinical Pharmacology
This experimental study explores the neuroprotective potential of curcumin in newborns with perinatal asphyxia using an animal model. The aim is to assess whether curcumin, as an accessible substance, can mitigate the effects of asphyxia in settings where hypothermia therapy is unavailable, while strengthening research capacity in translational neuroscience.
1. Morphometric Analysis of Intervertebral Disc Changes in Radicular Pain Syndrome and Lumbar Pain Syndrome
Project Lead: Prof. Dr. Zurifa Ajanović, Department of Human Anatomy
The project focuses on distinguishing age-related changes from pathological processes in disc degeneration, aiming to improve diagnostic approaches and understanding of clinical relevance.
2. Intermittent Fasting – A Promising Measure for Long-Term Heart Health?
Project Lead: Prof. Dr. Dina Kapić, Department of Histology and Embryology
This project investigates the effects of intermittent fasting (5:2 regimen) on biochemical and histological changes associated with cardiac aging, aiming to identify a potential non-pharmacological approach to healthier aging.
3. Investigation of the Association Between Oxidative Stress Levels and rs1061170 Polymorphism in Complement Factor H with Kidney Transplant Rejection
Project Lead: Assist. Prof. Dr. Lejla Alić Mehić, Department of Medical Biochemistry
In collaboration with the Medical University of Vienna, this project explores the role of FHR-1 and FHR-3 proteins in MDA epitope binding and complement activation, identifying a genetic variant that may serve as a diagnostic marker for transplant outcomes.
1. Protective Effect of Exogenous Melatonin on Metabolic and Reproductive Consequences of Chronic Inflammation in Polycystic Ovary Syndrome – A Rat Model Study
Project Lead: Prof. Dr. Emina Kiseljaković, Department of Medical Biochemistry
2. A New Possibility for Paracetamol Use – Neuroprotective Effects in Perinatal Asphyxia: Yes or No?
Project Lead: : Prof. Dr. Jasna Kusturica, Department of Pharmacology, Toxicology and Clinical Pharmacology
3. Combined PRP and HBOT Therapy as an Innovative Method for Treating Chronic Wounds
Project Lead:Prof. Dr. Lejla Burnazović-Ristić, Department of Pharmacology, Toxicology and Clinical Pharmacology
4. Introducing a Biological Marker into Forensic Practice as a Supplement to Macroscopic and Microscopic Organ Examination in Determining Cause of Death by Drowning
Project Lead: Assist. Dr. Emina Dervišević, Department of Forensic Medicine
1. Preclinical Study of the Protective Effects of Curcumin and Rosuvastatin on Gentamicin-Induced Hearing, Balance, and Kidney Damage – A New Chance to Reduce Disability Rates
Project Lead: Prof. Dr. Aida Kulo Ćesić, Department of Pharmacology, Toxicology and Clinical Pharmacology
2. Introduction and Optimization of a New Diagnostic Procedure in Forensic Practice
Project Lead: Assist. Dr. Emina Dervišević, Department of Forensic Medicine
3. Importance of the Triglyceride-Glucose Index and Lipid Parameters in Early Detection of Cardiovascular Risk in the Student Population
Project Lead: Prof. Dr. Sabaheta Hasić, Department of Medical Biochemistry
1. Implementation of FELASA trends in biomedical research – Artificial inteligence as an alternative to animal models for the research of selected pharmacological agents on the example of paracetamol: New possibility of paracetamol application-neuroprotective effects in perinatal asohyxia: yes or no?
Project Lead: Prof. Dr. Aida Kulo Ćesić, Department of Pharmacology, Toxicology and Clinical Pharmacology
1. Implementation of FELASA Trends in Biomedical Research – Artificial Intelligence as an Alternative to Animal Models for Studying Selected Pharmacological Agents Using Paracetamol as an Example: New Possibility of Paracetamol Application – Neuroprotective Effects in Perinatal Asphyxia: Yes or No?
Project Lead: Prof. Dr. Aida Kulo Ćesić, Department of Pharmacology, Toxicology and Clinical Pharmacology
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